What medicine can be taken to treat bladder sphincter relaxation?

For bladder sphincter relaxation, you can use Midodrine Hydrochloride Tablets, Tolterodine Tartrate Tablets, Solifenacin Succinate Tablets, Oxybutynin Hydrochloride Sustained-release Tablets, Doxazosin Mesylate Sustained-release Tablets and other drugs to improve symptoms as directed by your doctor. Bladder sphincter relaxation may be related to nerve damage, pelvic floor muscle dysfunction, changes in hormone levels and other factors. Drugs need to be selected based on the specific cause.

1. Midodrine Hydrochloride Tablets

Midodrine hydrochloride tablets are alpha receptor agonists that can improve urinary incontinence by enhancing the contractility of the bladder neck and urethral sphincter. This drug is suitable for sphincter relaxation caused by stress urinary incontinence or neurogenic bladder. Common adverse reactions include scalp numbness and increased blood pressure. Blood pressure needs to be monitored during medication, and patients with hypertension should use with caution.

2. Tolterodine tartrate tablets

Tolterodine tartrate is an anticholinergic drug that inhibits overactivity of the bladder and reduces episodes of urge urinary incontinence. It is suitable for patients with mixed urinary incontinence or overactive bladder, which may cause side effects such as dry mouth and constipation. Contraindicated in patients with glaucoma or gastrointestinal obstruction.

3. Solifenacin succinate tablets

Solifenacin succinate tablets relieve symptoms of frequent urination and urgency by selectively blocking bladder M3 receptors. It has a better effect on patients with overactive bladder detrusor and sphincter relaxation. Common adverse reactions include blurred vision and difficulty urinating. Patients with severe hepatic and renal insufficiency need to adjust the dose.

4. Oxybutynin hydrochloride sustained-release tablets

Oxybutynin hydrochloride sustained-release tablets can relax the bladder detrusor while increasing urethral resistance, and are suitable for patients with neurogenic bladder dysfunction. The sustained-release dosage form can reduce side effects such as dry mouth and drowsiness. Elderly people over 65 years old need to be wary of the impact on cognitive function when using it.

5. Doxazosin mesylate sustained-release tablets

Doxazosin mesylate sustained-release tablets, as α1 receptor blockers, can improve the urinary function of patients with prostatic hyperplasia and bladder outlet obstruction and indirectly reduce the burden on the sphincter. Please note the risk of orthostatic hypotension and it is recommended to take it before going to bed.

In addition to drug treatment, patients with bladder sphincter laxity should cooperate with pelvic floor muscle training such as Kegel exercises. Daily repeated contraction-relaxation exercises can help enhance muscle strength. Avoid consuming stimulating drinks such as caffeine and alcohol, and control your daily water intake to 1,500-2,000 ml, drinking in small amounts in portions. Overweight people need to lose weight to reduce abdominal pressure, and cross their legs when coughing or sneezing to reduce urine leakage. It is recommended to keep a urination diary to help doctors evaluate the efficacy and review urodynamic tests regularly. If conservative treatment is ineffective, surgical treatment options such as midurethral sling surgery can be considered.