Wearing tight clothing can lead to endometriosis!

 　　Uterus The incidence of endometriosis (EM) in the total population of women in developed countries is approximately 10%. Among them, peritoneal EM is the most common, and its cause is generally believed to be reflux of menstrual blood. Relevant factors are older age, previous parity, long-term use of LUD and vaginal plugs, as well as genetic and environmental factors. It is now discovered that tight clothing has a certain relationship with the occurrence of EM.
　　
　　Plasma colloid osmotic pressure helps the peritoneal fluid to be reabsorbed into the blood stream. The average interstitial fluid pressure formed is about 0.667kPa (5mmHg) lower than the atmospheric pressure, causing the fluid to slowly move up from the cervix to the uterine cavity, fallopian tube, and until the abdominal cavity becomes negative, and the interstitial fluid pressure in the abdominal cavity becomes negative. Correspondingly, there must be approximately equal positive solid tissue pressures. Measurements made with water-filled tension-free balloons in the stomach, colon, and abdominal cavity of dogs after anesthesia were, as expected, 0.667 kPa (5 rnmHg) greater than the osmotic pressure. The same is true for direct measurement of intra-abdominal pressure in humans. If the dog wears a corset, the dog's liver will have deformities and mild histological changes. In humans, it is called "corset liver", which is caused by intra-abdominal pressure that is higher than the liver for a long time. sexual dysfunction。

　　The peak intrauterine pressure in the first 3 days of the human menstrual cycle is 5.33-9.33kPa (40-70mmHg), with an average of 1. 07-6. 93kPa (8-52mmHg), Dysmenorrhea Women are taller. This intrauterine pressure, which is significantly higher than intra-abdominal pressure, is caused by uterine contractions. The utero-fallopian tube interface, which is as thin as a needle nose, also tends to close, so there is no reflux of menstrual blood. The uterine wall relaxes between contractions. If the cervix is ​​closed, the intrauterine pressure is approximately equal to the intra-abdominal pressure. If the intra-abdominal pressure that slowly increases suddenly decreases, even if the cervix is ​​not dilated, the uterine cavity with a thick and hard muscle wall will maintain the increased intrauterine pressure for a short period of time, and the pressure gradient from the uterine cavity to the fallopian tube cavity will change. It can cause the blood accumulated in the uterus and the shed endometrium to flow back. According to this reasoning, if the tight clothing worn reaches the point where the intra-abdominal solid tissue pressure continues to slightly increase, and the utero-fallopian tube interface happens to be loosened between two contractions when taking off the clothes, menstrual blood can flow backward. According to this reason, EM should be less common in women who do not wear clothes that increase intra-abdominal pressure.

　　It is known in modern times that EM is more common in developed countries than in developing countries. A Medline survey also found that there were only 4 cases of spontaneous EM reported in more than 20,000 articles in Indian medical journals in the past 30 years. There was also a large group of reports of EM in the scar after mid-trimester cesarean section. This is related to Indian women not wearing tights. The situation in China and Africa is similar, but developed countries had more than 5,000 EM reports and reviews during the same period (the United States accounted for half). Measuring gradient changes in fallopian tube and intra-abdominal pressure using thin catheters and micro-sensors ； The above reasoning was directly verified by using a tracer placed in the cervical canal and measuring the flow rate and amount of retrograde menstrual blood through scintillation imaging of the uterus and fallopian tube. To sum up, it can be considered that there is a certain relationship between tight clothing and the occurrence of endometriosis. From the perspective of the public healthy Women should also be advised not to wear tight clothing, at least during menstruation.